Adding a certain compound to certain chemical reactions, such as: 14432-12-3, 4-Amino-2-chloropyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 14432-12-3, blongs to pyridine-derivatives compound. category: pyridine-derivatives
(a) Sodium azide (1.31 g) and ammonium chloride (1.07 g) were added to a solution of 4-amino-2-chloropyridine (2 g) in dimethylformamide (20 ml) and the mixture was stirred at 110 C. for 10 hours. After the insoluble material was filtered off, the filtrate was concentrated under reduced pressure. The residue obtained was purified by silica gel column chromatography to give 1.83 g of 4-amino-2-azidopyridine, melting point 220 C. (decomposition). PMR(DMSO-d6 /TMS) delta: 6.55(2H, s), 6.67(1H,d,J=2 Hz), 6.76(1H, dd, J=2,8 Hz), 8.78(1H,d,J=8 Hz)
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,14432-12-3, its application will become more common.
Reference:
Patent; Yoshitomi Pharmaceutical Industries, Ltd.; US5478838; (1995); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem