Application of 19798-77-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 19798-77-7, name is 4-Amino-3-chloropyridine, molecular formula is C5H5ClN2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
In the second step, the first step of the product 2- [1- (pentyl-4-en-1-yl) -1H-indol-3-yl] acetic acid was added to dichloromethane (20 mL) and stirred at room temperature (1.27 g), stirred and dissolved;3-Chloro-4-aminopyridine (0.9 g) was added,DMAP (0.15 g), stirred at room temperature for 3 h;Add water (10mL) for 10min,The organic phase was stirred for 10 min and the organic phase was separated by column chromatography and eluted with ethyl acetate-petroleum ether (1: 3) to give red-brown gum N- (3 Yl) -2-yl] -2- (1- (3-pentyl-4-en-1-yl) -1H-indol-3-yl] acetamide (1.3 g).
According to the analysis of related databases, 19798-77-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Institute; Shi Jiangong; Guo Ying; Xu Chengbo; Ba Mingyu; Chen Minghua; Chen Qing; Zhu Chenggen; Tang Ke; Jiang Jiandong; Guo Jiamei; Guo Qinglan; Lin Sheng; Yang Yongchun; (45 pag.)CN107151231; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem