Reference of 609-71-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 609-71-2, name is 2-Oxo-1,2-dihydropyridine-3-carboxylic acid, molecular formula is C6H5NO3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
To a solution of the chlorophosphite (10) (1.121 g; 0.936 mmol) in toluene (7 ml) is added dropwise at 0 C. while stirring a solution of 2-hydroxynicotinic acid (0.506 g; 3.742 mmol) in a mixture of toluene (13 ml) and triethylamine (5.6 ml). The mixture is stirred at room temperature overnight and filtered, and the filtrate is concentrated under reduced pressure. The residue obtained is dried at 50 C./0. 1 mbar for 2 h and is used as obtained. Yield: 0.67 g (0.458 mmol; 49%).10117] Analysis (calc. for C74H74N4020P4=1463.30 g/mol): C, 60.92 (60.74) %; H, 5.02 (5.10) %; P, 8.57 (8.47)j0118] 31P-NMR (CD2C12): 115.1 (s) ppm. ?H-NMR (CD2C12): 1.18 (36H); 1.84 (6H); 3.08 (4H); 3.85 (4H); 7.008.63 (24H) ppm.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 609-71-2, 2-Oxo-1,2-dihydropyridine-3-carboxylic acid.
Reference:
Patent; EVONIK DEGUSSA GMBH; DYBALLA, Katrin Marie; FRANKE, Robert; (21 pag.)US2017/88569; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem