Analyzing the synthesis route of 271-63-6

At the same time, in my other blogs, there are other synthetic methods of this type of compound,271-63-6, 1H-Pyrrolo[2,3-b]pyridine, and friends who are interested can also refer to it.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 271-63-6, name is 1H-Pyrrolo[2,3-b]pyridine. A new synthetic method of this compound is introduced below., 271-63-6

(1) Add 7-azaindole and water to the reactor, stir for 45 minutes, add tetramethyl phosphonium and MFI zeolite, heat to 50C, stir and mix, add formaldehyde,After homogenization, microwave irradiation was performed for 2 hours, and the reaction was continued for 6 hours after stirring. After filtration, the precipitate was dissolved in methylene chloride. After filtration, the filtrate was distilled under reduced pressure and recrystallized to give 7-azaindole-3-methanol.;

At the same time, in my other blogs, there are other synthetic methods of this type of compound,271-63-6, 1H-Pyrrolo[2,3-b]pyridine, and friends who are interested can also refer to it.

Reference:
Patent; Dongguan Lianzhou Knowledge Property Right Scheduled Operations Management Co., Ltd.; Chen Dongjin; (6 pag.)CN107903261; (2018); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem