Adding a certain compound to certain chemical reactions, such as: 327056-62-2, 2-Cyano-5-fluoropyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 2-Cyano-5-fluoropyridine, blongs to pyridine-derivatives compound. name: 2-Cyano-5-fluoropyridine
The mixture of 5-fluoro-pyridine-2-carbonitrile (0.16 g,1.27mmol) and Pd/C (0.030 g, 10% wt) in 15 ml of MeOH and0.50 ml of concentrated HCl was placed under H2 which wasprovided by a balloon and stirred at RT for 4 h, filteredthrough Celite, condensed, the residue was purified byflash column chromatography. The titled compound wasobtained as a light yellowish solid. MS(ES+): 127.2 (freebase) (M+H)+ . Calc’d for C6H7FN2 (free base)- 126.13.
The synthetic route of 327056-62-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; AMGEN INC.; WO2006/12374; (2006); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem