Analyzing the synthesis route of 4-Acetylpyridine

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1122-54-9, 4-Acetylpyridine, other downstream synthetic routes, hurry up and to see.

Synthetic Route of 1122-54-9, Adding some certain compound to certain chemical reactions, such as: 1122-54-9, name is 4-Acetylpyridine,molecular formula is C7H7NO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1122-54-9.

Preparation of 4-Bromoacetylpyridine, HBr saltHBrBromine (24 g, 150 mmol) in 4 mL of 45% HBr was added drop wise under vigorous stirring to a solution at 70C of 4-acetyl-pyridine (18 g, 148 mmol) in acetic acid containing 45% of HBr (165 mL). The vigorously stirred mixture was kept at 700C for 3h. The mixture was cooled and the precipitate collected by filtration and washed with petroleum ether(40-65C)/methanol (1/1, 100 mL) to give 35.8 g of a white crystals of (85%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1122-54-9, 4-Acetylpyridine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; AB SCIENCE; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS); INSTITUT CURIE; WO2006/106437; (2006); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem