Electric Literature of 1796-84-5 ,Some common heterocyclic compound, 1796-84-5, molecular formula is C7H8N2O3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Step 1: 3-nitro-4-[2-(piperazine-1-yl)ethyl]aminopyridine. A mixture of 1-(2-aminoethyl)piperazine and 4-ethoxy-3-nitropyridine in CH3 CN was heated at reflux for 40 hours. The reaction mixture was cooled to ambient temperature and concentrated to give 3-nitro-4-[2-(piperazine-1-yl)ethyl]aminopyridine which was used without further purification.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1796-84-5, its application will become more common.
Reference:
Patent; Abbott Laboratories; US5654305; (1997); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem