Related Products of 766-16-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 766-16-5, name is 4-Fluoro-2-methylpyridine. This compound has unique chemical properties. The synthetic route is as follows.
A suspension of l-cyclopropyl-6-(lH-imidazol-4-yl)-3,3-dimethyl-lH-pyrrolo[3,2-c]pyridin- 2(3H)-one (80 mg), 4-fluoro-2-methylpyridine (42 mg) and cesium carbonate (185 mg) in acetonitrile (1 ml) was heated to reflux temperature for 3 h. The mixture was evaporated and the residue purified by flash chromatography (silica gel, 0% to 10% MeOH in dichloromethane) to give the title compound (59 mg, 55%) as a white foam. MS (ESI, m/z): 360.3 [(M+H)+].
According to the analysis of related databases, 766-16-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; HILPERT, Hans; KOLCZEWSKI, Sabine; LIMBERG, Anja; STOLL, Theodor; WO2015/177110; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem