Adding a certain compound to certain chemical reactions, such as: 52313-50-5, Picolinimidamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 52313-50-5, blongs to pyridine-derivatives compound. Safety of Picolinimidamide
Example 90 5-(2-Fluoro-4-methoxy-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine In a similar fashion using route 17 general procedure 55, pyridine-2-carboxamidine (100 mg, 0.83 mmol), 2-(2-fluoro-4-methoxy-benzyl)-malononitrile (186 mg, 0.91 mmol) and NaOMe (89 mg, 1.65 mmol) gave the title compound (14 mg, 5%) after purification by trituration from MeCN/Et2O.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,52313-50-5, its application will become more common.
Reference:
Patent; VIFOR (INTERNATIONAL) AG; US2012/202806; (2012); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem