Application of 53174-98-4, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 53174-98-4, name is Thieno[2,3-b]pyridine-2-carbaldehyde. A new synthetic method of this compound is introduced below.
General procedure: A solution of the p-toluenesulfonhydrazide (5.5 mmol) and the appropriate heterocarbonyl compound (5 mmol) in MeOH (12 mL) and 10% HCl (0.05 mL) was heated at reflux for 24 h. The reaction mixture was cooled to room temperature; the final product was filtered and purified by crystallization.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,53174-98-4, Thieno[2,3-b]pyridine-2-carbaldehyde, and friends who are interested can also refer to it.
Reference:
Article; Garcia-Carrillo, Mario Alfredo; Guzman, Angel; Diaz, Eduardo; Tetrahedron Letters; vol. 58; 20; (2017); p. 1952 – 1956;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem