Electric Literature of 53174-98-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 53174-98-4, name is Thieno[2,3-b]pyridine-2-carbaldehyde. This compound has unique chemical properties. The synthetic route is as follows.
Example 161 N-(4-{trans-2-[(thieno[2,3-b]pyridin-2-ylmethyl)amino]cyclopropyl}phenyl)-3-(trifluoromethyl)benzamide hydrochloride By a method similar to Example 65, the title compound (10 mg) was obtained from N-[4-(trans-2-aminocyclopropyl)phenyl]-3-(trifluoromethyl)benzamide hydrochloride (75 mg) and thieno[2,3-b]pyridine-2-carbaldehyde (44.6 mg). MS (API+): [M+H]+ 468.0. 1H NMR (300 MHz, CD3OD) delta 1.36-1.57 (2H, m), 2.41 (1H, ddd, J = 10.2, 6.5, 3.7 Hz), 3.01 (1H, dt, J = 7.6, 4.0 Hz), 4.73 (2H, s), 7.07 (2H, d, J = 8.7 Hz), 7.44-7.54 (2H, m), 7.61 (2H, d, J = 8.7 Hz), 7.70-7.79 (1H, m), 7.90 (1H, d, J = 7.9 Hz), 8.15-8.30 (3H, m), 8.58 (1H, dd, J = 4.7, 1.5 Hz).
According to the analysis of related databases, 53174-98-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Takeda Pharmaceutical Company Limited; TOMITA, Naoki; KAJII, Shigeo; CARY, Douglas Robert; TOMITA, Daisuke; IMAMURA, Shinichi; TSUCHIDA, Ken; MATSUDA, Satoru; HARA, Ryujiro; EP2743256; (2014); A1;,
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