Analyzing the synthesis route of 5470-70-2

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 5470-70-2, Methyl 6-methylnicotinate.

5470-70-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5470-70-2, name is Methyl 6-methylnicotinate. This compound has unique chemical properties. The synthetic route is as follows.

Step 1: PtO2 (3.00 g) was added to a methanol solution (200 mL) of methyl 6-methylpyridine-3-carboxylate(18.00g, 119.08 mmol), and then added with water (10mL) and hydrochloric acid (20mL); under H2 (50psi), the reaction solutionwas heated to 50C and stirred for 15 h. TLC showed that the reactants were completely consumed; then solid werefiltered, and the filtrate was concentrated under reduced pressure, residues were dissolved in toluol (100 mL), then thesolvent toluol was spin-dried to obtain methyl 6-methylpiperidyl-3-carboxylatewhich was yellow oily matter (18.00 g, yieldwas 96.15%). The value of C8H15NO2[M+H]+157 was calculated using MS ESI, was 157.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 5470-70-2, Methyl 6-methylnicotinate.

Reference:
Patent; Wuxi Fortune Pharmaceutical Co., Ltd; WU, Hao; MAO, Weiwei; FAN, Lili; DING, Charles Z.; CHEN, Shuhui; WANG, Fei; HU, Guoping; LI, Jian; (85 pag.)EP3248980; (2017); A1;,
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