Analyzing the synthesis route of 571188-59-5

According to the analysis of related databases, 571188-59-5, the application of this compound in the production field has become more and more popular.

Electric Literature of 571188-59-5, Adding some certain compound to certain chemical reactions, such as: 571188-59-5, name is tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate,molecular formula is C14H22N4O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 571188-59-5.

600 mg of Compound 5 was dissolved in 3 mL of toluene solution. 2 mL of a 1 mol/L solution of LiHMDS in tetrahydrofuran was added at 0 to 10 C and stirred for 1 h. At 0 to 10 C, 292 mg of a toluene solution of Compound 2 was added, and the reaction was slowly returned to room temperature for 5 hours.After the end of the reaction was monitored by HPLC, the reaction was quenched with 6 mL of saturated ammonium chloride. The organic phase was separated and dried over anhydrous sodium sulfate. An off-white solid with a yield of 54%.

According to the analysis of related databases, 571188-59-5, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Suzhou Pengxu Pharmaceutical Technology Co., Ltd.; Li Pixu; Wang Peng; Wei Qiang; (7 pag.)CN109553621; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem