Synthetic Route of 59146-67-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 59146-67-7, name is 5,6-Dimethylpicolinonitrile. This compound has unique chemical properties. The synthetic route is as follows.
5,6-Dimethyl-2-pyridinecarbonitrile 1 -oxide; To a solution of 5,6-dimethyl-2-pyridinecarbonitrile (3.68 g, Ref: Guay et al., Bioorg. Med. Chem. Letters, 8 (5), 453. (1998)) in chloroform (25 ml) was added dropwise a solution of m-chloroperbenzoic acid (7.35 g) in chloroform (75 ml) and the solution stirred at ambient temperature for 40 hours. Sodium sulphite (2.4 g) was added and the mixture stirred for 1 hour, filtered and the solid washed with dichloromethane. The filtrate was washed with saturated sodium bicarbonate (50 ml) and water (50 ml), dried (MgSO4) and concentrated in vacuo. The residue was recrystallised from ether to afford the title compound (3.44 g, 83%) as a white solid. LC/MS [MH+] = 149, RT = 1.30 min.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 59146-67-7, 5,6-Dimethylpicolinonitrile.
Reference:
Patent; GLAXO GROUP LIMITED; WO2006/66968; (2006); A1;,
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