Synthetic Route of 6318-51-0, Adding some certain compound to certain chemical reactions, such as: 6318-51-0, name is (4-Chlorophenyl)(pyridin-2-yl)methanone,molecular formula is C12H8ClNO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6318-51-0.
2.0 g (4-chlorophenyl)(2-pyridyl)methanone,Dissolved in 15 mL of hydrogen peroxide (30% aqueous solution in mass concentration)Add 5mL of acetic acid,The reaction was heated to 85C for 12h and TLC detected the progress of the reaction.Until the reaction of the raw material is complete,Add saturated sodium bicarbonate solution,Dichloromethane extraction,Wash, combine the organic phase,Drying over anhydrous sodium sulfate, filtration,Remove the solvent under reduced pressureA white solid of 2.1 g was obtained with a yield of 95%.
According to the analysis of related databases, 6318-51-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; China Three Gorges University; Zhou Haifeng; Wang Baigui; Liu Qixing; Jiang Xiaolan; (7 pag.)CN106831549; (2017); A;,
Pyridine – Wikipedia,
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