Related Products of 6945-67-1, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.6945-67-1, name is 2-Bromo-4-nitropyridine, molecular formula is C5H3BrN2O2, molecular weight is 202.99, as common compound, the synthetic route is as follows.
2-bromo-4-nitropyridine(1.00g, 4.93mmol),4,4-difluoropiperidine hydrochloride(1.16g, 7.39mmol) and cesium carbonate (4.82g, 14.78mmol) were dissolved in 20mL 1,4-Dioxane solution, heated to 100 reaction overnight, LC-MS detection.The reaction is completed, cooled to room temperature, filtered,The filtrate was concentrated and purified by column chromatography to obtain the title compound.
Statistics shows that 6945-67-1 is playing an increasingly important role. we look forward to future research findings about 2-Bromo-4-nitropyridine.
Reference:
Patent; Nanjing Shenghe Pharmaceutical Co., Ltd.; Wang Yong; Zhao Liwen; Wang Yazhou; Quan Xu; Liu Haixuan; Wang Xiaowei; Zhang Yan; Li Xue; Cao Chen; Guo Zhuang; Lv Kunzhi; Wang Hai; Zheng Guochuang; (126 pag.)CN111196804; (2020); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem