Related Products of 76015-11-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 76015-11-7, name is 3-Methoxy-2-methylpyridin-4(1H)-one. This compound has unique chemical properties. The synthetic route is as follows.
In a four-necked flask equipped with a mechanical stirrer, a reflux condenser, and a thermometer,230 grams of phosphorus oxychloride, 27.8 grams of 3-methoxy-2-methyl-4-pyrone, stirring slowly heated to 60-70 C, heat 10h,Cooling to 0-10 C, adding 60 g DMF, stirring 2h, layered,The lower organic layer was collected to give Vilsmeier reagent.The upper layer was poured into 50 g of ice-water mixture and the hydrolysis temperature was controlled at -5-5 C.Stirring 1h hydrolysis is complete, with 30% liquid alkali 20-30 adjust the pH to 12,Extracted with methylene chloride,Distillation gave the desired product4-Chloro-3-methoxy-2-methyl-4-pyridin 26.5 g,Using 3-methoxy-2-methyl-4-pyrone meter, mass yield of 95.3%.
According to the analysis of related databases, 76015-11-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; jiangsu yuxiang chemical co. ltd; Zhejiang University of Science and Technology; LI, GUONENG; Zhang, ZHIGUO; Cheng, Yun Tao; Zhong, Xu Hui; Li, Qing Long; Cheng, hongweid; (7 pag.)CN103483248; (2016); B;,
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