Reference of 823221-93-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 823221-93-8, name is 5-Bromo-2-chloro-4-(trifluoromethyl)pyridine, molecular formula is C6H2BrClF3N, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: To a solution of halogenopyridine (1.0 eq) in indicated solvent at rt was added hydrazinehydrate (1-10 eq.). Reaction mixture was stirred at the indicated temperature for theindicated time. Solvents were concentrated under vacuum. Water or saline solution was then added Precipitate that formed was filtered off, washed with water and dried under vacuum yielding 2-hydrazinylpyridi ne.
According to the analysis of related databases, 823221-93-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; RICHTER GEDEON NYRT.; ORION CORPORATION; HAIKARAINEN, Anssi; JOUBERT, Muriel; KAROLYI, Benedek; KAeSNAeNEN, Heikki; PASSINIEMI, Mikko; POHJAKALLIO, Antti; SZANTO, Gabor; VAISMAA, Matti; (97 pag.)WO2019/43635; (2019); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem