Synthetic Route of 29681-43-4, Adding some certain compound to certain chemical reactions, such as: 29681-43-4, name is Methyl 4-methoxypyridine-2-carboxylate,molecular formula is C8H9NO3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 29681-43-4.
A solution of lithium aluminium hydride (1M in diethyl ether, 16 ml) was added dropwise to a stirred mixture of methyl 4-methoxypyridine-2-carboxylate (2.7 g) and diethyl ether (50 ml). The resultant mixture was heated to reflux for 1 hour. The mixture was treated with potassium sodium tartrate tetrahydrate and extracted with ethyl acetate. The organic phase was dried (MgSO4) and evaporated. The residue was purified by column chromatography using increasingly polar mixtures of methylene chloride and methanol as eluent to give 4-methoxypyrid-2-ylmethanol (0.8 g); NMR Spectrum: 3.62 (s, 3H), 4.51 (d, 2H), 5,34 (broad t, 1H), 6.8 (m, 1H), 6.99 (d, 1H), 8.27 (d, 1H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 29681-43-4, Methyl 4-methoxypyridine-2-carboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Zeneca Limited; US5821246; (1998); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem