Facile One-Pot Assembly of Push-Pull Imines by a Selective C-F Substitution Process in Aryl Fluorides was written by Anga, Srinivas;Chandra, Shubhadeep;Sarkar, Pallavi;Das, Shubhajit;Mandal, Debdeep;Kundu, Abhinanda;Rawat, Hemant;Schulzke, Carola;Sarkar, Biprajit;Pati, Swapan K.;Chandrasekhar, Vadapalli;Jana, Anukul. And the article was included in European Journal of Organic Chemistry in 2020.Computed Properties of C5F5N The following contents are mentioned in the article:
Herein, we report the synthesis of a series of push-pull imines by considering cyclic diamino substituent at the C-center and fluoroaryl substituent at the N-center. This has been achieved by a selective aromatic nucleophilic substitution of different fluoroarenes by N-H-substituted N-heterocyclic imines (NHIs) at ambient conditions without any addnl. reagent. Solid-state mol. structure anal. reveals the elongation of the central C-N bond of the imine functionality, which is consistent with the push-pull nature of these imines. The push-pull nature of these imines is further validated by computational studies. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Computed Properties of C5F5N).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Computed Properties of C5F5N