Electric Literature of 112193-41-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 112193-41-6, name is 5-Bromonicotinohydrazide, molecular formula is C6H6BrN3O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
EXAMPLE 102 4-[1-(3-Aminopropyl)-5-fluoro-indol-3-yl]-5-(5-bromo-pyridin-3-yl)-2,4-dihydro-[1,2,4]triazol-3-one hydrochloride The title compound was prepared by the method described in Example 45 starting from the product of Example 45d) and 5-bromo-nicotinic acid hydrazide. 1H NMR (400 MHz, DMSO-d6): delta12.45 (1H, s); 8.68 (1H, d); 8.48 (1H, d); 8.00 (1H, m); 7.89 (3H, bs); 7.80 (1H, s); 7.70 (1H, m); 7.16 to 7.09 (2H, m); 4.35 (2H, m); 2.75 (2H, m); 2.04 (2H, m). APCI-MS m/z: 431 [MH+].
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 112193-41-6, 5-Bromonicotinohydrazide.
Reference:
Patent; Astrazeneca AB; US6492406; (2002); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem