115473-15-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 115473-15-9, name is 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one hydrochloride. This compound has unique chemical properties. The synthetic route is as follows.
Example-22: Preparation of 5-(a-cycIopropylcarbonyl-2-fluorobenzyI)-2-oxo- 2,4,5,6,7,7a-hexahydro thieno[3,2-c] pyridine hydrochloride:A mixture of 5,6,7,7a-tetrahydro-4H-thieno[3,2-c]-pyridin-2-one-hydrochloride (100 grams), potassium carbonate (63.5 grams) and acetonitrile (1000 ml) was stirred for 30 minutes at 25-30C. 2-bromo-l-cyclopropyl-2-(2-fluorophenyl) ethanone (66 grams) in acetonitrile (30 ml) was added to the reaction mixture and stirred for 7 hours at 25-30C. The reaction mixture was filtered and removed the precipitated solid. The filtrate was absorbed with silica gel and passed the material through silica gel bed using, ethyl acetate and cyclohexane in 1 :1 ratio. Distilled the solvent completely under reduced pressure. 650 ml of acetone was added to the obtained compound and cooled the reaction mixture to 25-30C. Ethyl acetate hydrochloride^ 75 ml) was added to the obtained compound and stirred for 1 hour. Filtered the precipitated solid and dried the compound.Yield: 65 gms; MR: 178-183C
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 115473-15-9, 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one hydrochloride.
Reference:
Patent; MSN LABORATORIES LIMITED; SATYANARAYANA REDDY, Manne; THIRUMALAI RAJAN, Srinivasan; ESWARAIAH, Sajja; RAMA SUBBA REDDY, Karamala; KONDAL REDDY, Bairy; VENKAT REDDY, Ghojala; WO2011/42918; (2011); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem