Application of 1570-45-2

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1570-45-2, Ethyl isonicotinate, and friends who are interested can also refer to it.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1570-45-2, name is Ethyl isonicotinate, molecular formula is C8H9NO2, molecular weight is 151.16, as common compound, the synthetic route is as follows.COA of Formula: C8H9NO2

In an autoclave, the reactant and Ru(acac)3 were dissolved with 1.4 equivalents of tris(diphenylphosphinomethyl)ethane in isopropanol, and converted at 150 C. and 150 bar of hydrogen pressure for 24 h. After the reaction, the reaction mixture was analyzed by gas chromatography.Conversion, selectivity and yield were determined by means of gas chromatography. Substrates, batch sizes and analysis are compiled in Table 1.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1570-45-2, Ethyl isonicotinate, and friends who are interested can also refer to it.

Reference:
Patent; BASF SE; US2009/43102; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem