Synthetic Route of 1603-40-3, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1603-40-3, name is 3-Methylpyridin-2-amine. A new synthetic method of this compound is introduced below.
A. Preparation of (X) where Y and Z are Hydrogen A solution of 2-amino-3-methylpyridine (10.8 g) and di-tert-butyl dicarbonate (21.8 g) in tetrahydrofuran was heated under reflux for 12 hours. Evaporation afforded a solid which was recrystallized from ether-tetrahydrofuran to yield 2-(t-butoxycarbonylamino)-3-methylpyridine (10.2 g), a compound of Formula (X), m.p. 132-133 C.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,1603-40-3, 3-Methylpyridin-2-amine, and friends who are interested can also refer to it.
Reference:
Patent; Syntex (U.S.A.) Inc.; US5212195; (1993); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem