Related Products of 178876-86-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 178876-86-3, name is Methyl 5-bromo-6-oxo-1,6-dihydropyridine-2-carboxylate. This compound has unique chemical properties. The synthetic route is as follows.
Pd(PPh3)2C12 (30 mg, 0.0424 mmol) was added to a nitrogen flushed mixture of methyl 5- bromo-6-oxo- 1 ,6-dihydropyridine-2-carboxylate (98.4 mg, 0.424 mmo 1), 4- isopropylphenylacetylene (92 mg, 0.636 mmol), Cul (16.1 mg, 0.0848 mmol) and Et3N (600 jil) in THF (1.5 ml) and the mixture was heated at 100 C in microwave reactor for 15 mm. Solvent evaporated and residue purified by flash chromatography using 20-33% EtOAc aseluent. Yield: 55.5 mg (44%); beige solid.
According to the analysis of related databases, 178876-86-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; KANCERA AB; HAMMER, Kristin; JOeNSSON, Mattias; KRUeGER, Lars; (230 pag.)WO2017/108282; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem