Reference of 34107-46-5 ,Some common heterocyclic compound, 34107-46-5, molecular formula is C7H9NO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Chromium trioxide (11.5 g) is slowly added to 170 ml of pyridine at 20C, and 10 g of the crude 5-hydroxy-methyl-2-methylpyridine in 70 ml of pyridine is added in one portion to the complex. The temperature is raised to reflux temperature for 2 hours, and the mixture is refluxed for 1.5 hours. After cooling, 250 ml of water is added, and the mixture is extracted with five 150-ml portions of diethyl ether. The combined extracts are dried over magnesium sulfate and concentrated to give 4.2 g of crude 6-methyl-3-pyridinecarbaldehyde.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,34107-46-5, its application will become more common.
Reference:
Patent; Dainippon Pharmaceutical Co., Ltd.; EP210782; (1991); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem