Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 180748-30-5, name is (4-Chloropyridin-2-yl)methanamine. This compound has unique chemical properties. The synthetic route is as follows. Product Details of 180748-30-5
[0411] To (4-chloro-2-pyridyl)methanamine (59, 0.51 g, 3.58 mmol) in dichloromethane (50 mL) was added l-isothiocyanato-4-nitro-benzene (65, 0.66 g, 3.65 mmol). The reaction mixture was stirred at room temperature for about 1 hour. LCMS showed the reaction was complete. The reaction was concentrated, and washed with ethyl acetate and hexane to give product (63).
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Reference:
Patent; PLEXXIKON INC.; ZHANG, Jiazhong; POWERS, Hannah; ALBERS, Aaron; PHAM, Phuongly; WU, Guoxian; BUELL, John; SPEVAK, Wayne; GUO, Zuojun; WALLESHAUSER, Jack; ZHANG, Ying; (229 pag.)WO2019/183145; (2019); A1;,
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