With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.16665-38-6, name is (4-Methoxypyridin-2-yl)methanol, molecular formula is C7H9NO2, molecular weight is 139.15, as common compound, the synthetic route is as follows.Quality Control of (4-Methoxypyridin-2-yl)methanol
(4) 2-Chloromethyl-4-methoxypyridine hydrochloride This was prepared by the method of Baker et. al., J. Chem. Soc., Chem. Comm., 3598, 1958, but starting with 2-hydroxymethyl-4-methoxypyridine (as prepared in (3) above, 44.05 g, 0.317 mole) and thionyl chloride (500 ml) to give the title compound as a reddish solid, 46 g (75%) which was used directly in the following preparation without further purification.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,16665-38-6, (4-Methoxypyridin-2-yl)methanol, and friends who are interested can also refer to it.
Reference:
Patent; Pfizer Inc.; US4562197; (1985); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem