Adding a certain compound to certain chemical reactions, such as: 52378-63-9, (3-Aminopyridin-2-yl)methanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Quality Control of (3-Aminopyridin-2-yl)methanol, blongs to pyridine-derivatives compound. Quality Control of (3-Aminopyridin-2-yl)methanol
ii. A solution of sodium nitrite (2.38 g) in water (10 ml) was added dropwise to a mixture of 3-amino-2-hydroxymethylpyridine (4.8 g), aqueous hydrochloric acid (48%, 10 ml) and water (5 ml) stirred at 0 – 5. This solution was added to a hot solution of cuprous chloride (2.5 g) in conc. hydrochloric acid and the mixture was heated on a steam-bath for 0.5 hours, diluted with water and saturated with hydrogen sulphide. The mixture was filtered, concentrated and extracted with chloroform and the chloroform extract was evaporated to give 3-chloro-2-hydroxymethylpyridine (3.7 g) m.p. 42- 44 (from n-pentane).
The synthetic route of 52378-63-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Smith Kline & French Laboratories Limited; US4056621; (1977); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem