As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 350-03-8, name is 1-(Pyridin-3-yl)ethanone, molecular formula is C7H7NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Computed Properties of C7H7NO
General procedure: Definite quantities of catalyst, chiral diamine, base, solvent, and heteroaromatic methyl ketones were placed into a 60mL stainless steel autoclave equipped with a magnetic stirrer bar. The autoclave was purged with hydrogen three times and the hydrogen pressure was increased to the desired level. The mixture was then stirred at room temperature for a suitable time. At the end of the reaction, the reactor was decompressed. Finally, the products were separated by centrifugation and analyzed by a GC instrument with an FID detector and beta-DEX120 capillary column. The ee value was calculated from the equation: ee (%)=100¡Á(S-R)/(S+R).
With the rapid development of chemical substances, we look forward to future research findings about 350-03-8.
Reference:
Article; Li, Chun; Zhang, Lin; Zheng, Congye; Zheng, Xueli; Fu, Haiyan; Chen, Hua; Li, Ruixiang; Tetrahedron Asymmetry; vol. 25; 10-11; (2014); p. 821 – 824;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem