Electric Literature of 911434-05-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 911434-05-4, name is 5-Bromo-2-methyl-3-nitropyridine. This compound has unique chemical properties. The synthetic route is as follows.
A mixture of T-3 (13.2 g, 60.8 mmol) and iron powder (11.50 g, 205.9 mmol) in acetic acid (150 mL) is warmed at reflux. After 2 hours, the reaction is diluted with Et2O (100 mL) and EtOAc (250 mL) and filtered through filter agent washing with ethyl acetate. The filtrate is diluted with water (200 mL) made basic with first K2CO3 and then NaHCO3 and extracted with EtOAc (3 x 150 mL). The combined organic layers are washed with saturated aqueous NaHCO3 (100 mL), brine (2 x 100 mL), dried over magnesium sulfate, filtered and concentrated to provide T-4.
According to the analysis of related databases, 911434-05-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BETAGERI, Rajashekhar; COOK, Brian, Nicholas; DISALVO, Darren; HARCKEN, Christian; KUZMICH, Daniel; LIU, Pingrong; LORD, John; MAO, Can; RAZAVI, Hossein; WO2012/87782; (2012); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem