The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 915107-31-2, name is Methyl 6-chloro-5-methoxynicotinate. This compound has unique chemical properties. The synthetic route is as follows. Quality Control of Methyl 6-chloro-5-methoxynicotinate
Example 3. 3-Cyano-1-[6-(3,3-difluoro-pyrrolidin-1-yl)-5-methoxy-pyridin-3-ylmethyl]-1 H-pyrazole-4-carboxylic acid {l-amino-isoquinolin-6-ylmethyl)-amide {6-Chloro-S-methoxy-pyridin-3-yl)-methanol To a stirred solution of 6-chloro-5-methoxy-nicotinic acid methyl ester (0.5 g, 2.48 mmol) in anhydrous THF (20 mL) cooled to 0 C under nitrogen, was added UAIH4 (104 mg, 2.73 mmol). The reaction was allowed to warm to rt. The reaction was cooled to 0 C and quenched with water. Potassium sodium tartrate (Rochelle’s salt) was added and the mixture was filtered through Celite and washed with EtOAc (20 mL). The filtrate was separated and the aqueous extracted with EtOAc (20 mL). The combined organic layers were washed with brine (50 ml), dried over MgSO and the solvent removed in vacuo. The residue was purified by automated FC (EtOAc/petrol) to afford (6-chloro-5-methoxy-pyridin-3-yl)- methanol (710 mg, 82% yield) [MuEta]+ = 173.7
With the rapid development of chemical substances, we look forward to future research findings about 915107-31-2.
Reference:
Patent; KALVISTA PHARMACEUTICALS LIMITED; SMITH, Alun John; NOVAK, Andrew Richard; EVANS, David Michael; EDWARDS, Hannah Joy; STOCKS, Michael John; DAVIE, Rebecca Louise; MARSH, Sally Louise; HODGSON, Simon Teanby; (0 pag.)WO2016/83816; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem