Recently I am researching about TRANSFER HYDROGENATION; RADICAL IONS; LIGHT; ALKENES; MARKOVNIKOV; FUNCTIONALIZATION; PHOTOCHEMISTRY; PHOTOCATALYSIS; GENERATION; COMPLEXES, Saw an article supported by the ARC Industrial Transformation Training Centre Post-Doctoral FellowshipAustralian Research Council; University of Melbourne, Melbourne Research Scholarship (MRS); University of MelbourneUniversity of Melbourne; CSIROCommonwealth Scientific & Industrial Research Organisation (CSIRO); ARCAustralian Research Council [IC1701000020]. Safety of Phenyl(pyridin-2-yl)methanone. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Czyz, ML; Taylor, MS; Horngren, TH; Polyzos, A. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone
The conversion of olefin feedstocks to architecturally complex alkanes represents an important strategy in the expedient generation of valuable molecules for the chemical and life sciences. Synthetic approaches are reliant on the electrophilic activation of unactivated olefins, necessitating functionalization with nucleophiles. However, the reductive functionalization of unactivated and less activated olefins with electrophiles remains an ongoing challenge in synthetic chemistry. Here, we report the nucleophilic activation of inert styrenes through a photoinduced direct single electron reduction to the corresponding nucleophilic radical anion. Central to this approach is the multiphoton tandem photoredox cycle of the iridium photocatalyst [Ir(ppy)(2)(dtb-bpy)]PF6, which triggers in situ formation of a high-energy photoreductant that selectively reduces styrene olefinic it bonds to radical anions without stoichiometric reductants or dissolving metals. This mild strategy enables the chemoselective reduction and hydrofunctionalization of styrenes to furnish valuable alkane and tertiary alcohol derivatives. Mechanistic studies support the formation of a styrene olefinic radical anion intermediate and a Birch-type reduction involving two sequential single electron transfers. Overall, this complementary mode of olefin activation achieves the hydrofunctionalization of less activated alkenes with electrophiles, adding value to abundant olefins as valuable building blocks in modern synthetic protocols.
Safety of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Czyz, ML; Taylor, MS; Horngren, TH; Polyzos, A or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem