Arora, Santosh; Talwar, Dinesh; Singh, Manjeet; Sahoo, Subash C.; Sharma, Rohit published the artcile< Second sphere coordination in orthonitrophenolate binding: Synthesis, biological, cytotoxic and X-ray structural studies of [Co(bpy)2CO3](C6H4NO3)·3H2O>, Computed Properties of 366-18-7, the main research area is crystal structure cobalt bipyridine carbonato orthonitrophenolate; cobalt bipyridine carbonato nitrophenolate preparation cytotoxic antimicrobial activity.
A new Co (III) complex salt [Co(bpy)2CO3](ONP)·3H2O (1) where ONP = orthonitrophenolate/C6H4NO3 was synthesized to explore [Co(bpy)2CO3]+ cation as a new host for orthonitrophenolate anion. The newly synthesized complex salt was then characterized by elemental anal., spectroscopic techniques (UV-Visible, FTIR, 1H NMR) and solubility product measurement. Single crystal x-ray structure studies of 1 revealed one 2-nitrophenolate anion, one [Co(bpy)2CO3]+cation and three H2O mols. of crystallization in the solid state. The structural studies revealed that a strong network of H bonding interactions O-H···O (water/phenolate), O-H···O (water/H2O), O-H···O (water/carbonate) stabilize the crystal lattice. Newly synthesized complex 1 was scrutinized for antimicrobial activity and the results revealing a modest activity. The synthesized compound was screened for anticancer activity against PANC-1 cells using MTT colorimetric assay.
Journal of Molecular Structure published new progress about Antibacterial agents. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Computed Properties of 366-18-7.