Arya, Kritika; Kumar, Sudesh; Arya, Anand Kumar; Kumar, Mahendra published the artcile< Ionic Liquid [PyN(CH2)4SO3H][CH3PhSO3] Mediated & Promoted Eco-Friendly One-Pot Domino Synthesis of Benzothiazolopyrano/Chromenopyrimidine Derivatives>, Application In Synthesis of 21876-43-7, the main research area is benzothiazolopyranopyrimidinone preparation green chem; aldehyde aminobenzothiazole pyrone multicomponent domino heterocyclization pyridinium ionic liquid; benzothiazolochromenopyrimidinone preparation green chem; hydroxycoumarin aldehyde aminobenzothiazole multicomponent domino heterocyclization pyridinium ionic liquid; pyridinium toluenesulfonic acid ionic liquid catalyst preparation.
The pyridinium based p-toluenesulfonic acid functionalized [Py(CH2)4SO3H][CH3PhSO3] ionic liquid has been employed as eco-friendly solvent cum promoter for the multicomponent domino heterocyclization of substituted 2-aminobenzothiazoles I (R1 = H, Me; R2 = H, Me; R3 = H, Me, Br; R4 = H, Me) with 4-hydroxy-6-methyl-2-pyrone/4-hydroxycoumarin and aryl aldehydes 4-R5C6H4CHO (R5 = MeO, Cl) to produce benzothiazolo[2,3-b]pyrano [3,4-e]pyrimidin-4-ones II and benzothiazolo[2,3-b]chromeno[3,4-e]pyrimidin-6-ones III in excellent yields. The Bronsted acidic ionic liquid could be reused five-times without a significant loss of catalytic activity. The protocol proves to be efficient and facile in terms of high yields, operational simplicity, reduced reaction time and ease of recovery of the reaction medium.
Current Organocatalysis published new progress about Benzothiazoles Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 21876-43-7 belongs to class pyridine-derivatives, and the molecular formula is C9H13NO3S, Application In Synthesis of 21876-43-7.