An article Synthesis of novel Schiff bases using green chemistry techniques; antimicrobial, antioxidant, antiurease activity screening and molecular docking studies WOS:000458612300045 published article about MICROWAVE-ASSISTED SYNTHESIS; IN-VITRO; UREASE; DERIVATIVES; COMPLEXES; INHIBITION; HYDRAZONES; ASSAY in [Mermer, Arif; Demirbas, Neslihan; Demirbas, Ahmet; Sirin, Yakup] Karadeniz Tech Univ, Dept Chem, TR-61000 Trabzon, Turkey; [Uslu, Harun] Inonu Univ, Fac Pharm, Dept Pharmaceut Chem, TR-44280 Malatya, Turkey; [Ceylan, Sule] Artvin Coruh Univ, Dept Occupat Hlth & Safety, Fac Med Sci, TR-08000 Artvin, Turkey in 2019.0, Cited 48.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1. Application In Synthesis of 3-Pyridinecarboxaldehyde
Schiff base derivatives were synthesized in this study via conventional, microwave irradiation and ultrasound sonication methods. Optimization conditions were examined for several parameter such as solvent, reaction time and yield. After determining the optimization conditions, the compounds were synthesized by using ultrasound sonication. The structures of the synthesized compounds were examined by spectral data, and the antiurease, antioxidant and antimicrobial activities of the Schiff bases derivatives were investigated due to the imine group (-C=N-) and promising results were obtained. The enzyme inhibitory potentials of these compounds were further validated through molecular docking studies. Also, In Silico ADME prediction studies were calculated for compounds. (C) 2019 Elsevier B.V. All rights reserved.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem