Recommanded Product: 4,4′-Dimethyl-2,2′-bipyridineIn 2019 ,《Synthesis, photophysics and the binding studies of rhenium(I) diimine surfactant complexes with serum albumins: A spectroscopic and docking study approach》 appeared in Journal of Luminescence. The author of the article were Balakrishnan, Gopalakrishnan; Rajendran, Thangamuthu; Murugan, Krishnan Senthil; Ganesan, Muniyandi; Sivasubramanian, Veluchamy Kamaraj; Rajagopal, Seenivasan. The article conveys some information:
Synthesis of the four rhenium(I) diimine surfactant complexes of the type fac-[Re(CO)3 (α-diimine){4-C11py}] CF3SO31a-1d (α-diimine = 2,2′-bipyridine) (a), 4,4′-di-methyl-2,2′-bipyridine (b), 4,4′-di-tert-butyl-2,2′-bipyridine (c) 4,4′-dinonyl-2,2′-bipyridine (d) and 4-C11py = (py-4-(CH2)10CH3) has been reported. In vitro protein (HSA and BSA) binding studies confirmed the binding affinity of the complexes toward the drug binding sites of subdomain IIA and IIIA, confirmed by spectral studies and mol. docking. The steady-state and time-resolved fluorescence spectra confirm that the static quenching, due to complex formation, is the dominant mechanism for fluorescence quenching. Mol. docking studies prove that hydrophobic interaction makes a predominant contribution even though hydrogen bonding does exist, and hence 1b, 1c and 1d exhibit stronger binding relative to 1a. The synchronous fluorescence and CD spectral studies show that these Re(I) complexes can induce conformational changes in the proteins. Finally, the distance, r, between donor (proteins) and acceptor (Re (I) complexes) obtained through FRET study is in the range 4.5-5.2 nm. The results came from multiple reactions, including the reaction of 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Recommanded Product: 4,4′-Dimethyl-2,2′-bipyridine)
4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.Recommanded Product: 4,4′-Dimethyl-2,2′-bipyridine Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.