In 2019,Angewandte Chemie, International Edition included an article by Bao, Xu; Wang, Qian; Zhu, Jieping. Product Details of 94928-86-6. The article was titled 《Dual Photoredox/Copper Catalysis for the Remote C(sp3)-H Functionalization of Alcohols and Alkyl Halides by N-Alkoxypyridinium Salts》. The information in the text is summarized as follows:
Under mild dual photoredox/copper catalysis, the reaction of N-alkoxypyridinium salts with readily available silyl reagents (TMSN3, TMSCN, TMSNCS) afforded δ-azido, δ-cyano, and δ-thiocyanato alcs. HOCH(R)(CH2)2C(R1)(R2)(R3) [R = H, Me, Et; R1 = n-Bu, Ph, (CH2)2OBn, etc.; R2 = H, Me; R1R2 = (CH2)4, (CH2)5; R3 = N3, CN, SCN] in high yields. The reaction proceeded through a domino process involving alkoxy radical generation, 1,5-hydrogen atom transfer (1,5-HAT) and copper-catalyzed functionalization of the resulting C-centered radical. Conditions for catalytic enantioselective δ-C(sp3)-H cyanation were also documented. In the experiment, the researchers used fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Product Details of 94928-86-6)
fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Product Details of 94928-86-6