Barnett, Kerry L. published the artcileAir-Stable [(R3P)PdCl2]2 Complexes of Neopentylphosphines as Cross-Coupling Precatalysts: Catalytic Application and Mechanism of Catalyst Activation and Deactivation, Recommanded Product: 2-Pyridinylboronic acid, the publication is Organometallics (2018), 37(9), 1410-1424, database is CAplus.
Air-stable [(R3P)PdCl2]2 complexes with di-tert-butylneopentylphosphine (DTBNpP, 1a) or trineopentylphosphine (TNpP, 1b) ligands were applied to Suzuki cross-coupling reactions, and the mechanism of their conversion to the active LPd(0) catalyst species was studied. Precatalysts 1a,b provide effective catalysts for Suzuki cross-coupling of aryl bromides at room temperature, even when the reactions were performed in air. The precatalyst systems provided much higher activity catalysts in toluene/H2O in comparison to MeCN/H2O. Precatalyst loadings could be decreased by a factor of 50 in toluene in comparison to MeCN, while achieving equal or better yields. In MeCN/H2O, ligand metalation to form a [(κ2-P,C-DTBNpP)PdX]2 palladacycle was found to compete with formation of the active Pd(0) species. The palladacycle shows low catalytic activity; thus, its formation represents a catalyst deactivation pathway. In toluene, clean formation of the active Pd(0) species occurs without competitive palladacycle formation. The improved selectivity to form the active Pd(0) species in toluene appears to account for the higher activity of the precatalysts in toluene/H2O.
Organometallics published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Recommanded Product: 2-Pyridinylboronic acid.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem