Bazyar, Zahra; Hosseini-Sarvari, Mona published the artcile< Au@ZnO Core-Shell: Scalable Photocatalytic Trifluoromethylation Using CF3CO2Na as an Inexpensive Reagent under Visible Light Irradiation>, Application In Synthesis of 3796-23-4, the main research area is trifluoromethylated compound preparation; photocatalytic trifluoromethylation gold nanoparticle modified zincoxide photocatalyst.
Trifluoromethylation is of significant importance for the synthesis of many small mols. vital for medicinal and agrochem. research. The importance of the CF3 group as well as the related synthetic challenges is so evident that many reagents have been reported for the synthesis of trifluoromethylated compounds, but these typical reagents are expensive and the methods for preparing them are difficult. Here, we report a new scalable and operationally simple trifluoromethylation reaction using sodium trifluoroacetate as a reagent and Au-modified ZnO as a photocatalyst under visible light irradiation The reaction proceeds via trifluoromethylation of a broad range of aryl halides, arylboronic acids, and arene and heteroarene substrates. Some pharmaceutical and agrochem. compounds have been trifluoromethylated directly to demonstrate the applicability of the method.
Organic Process Research & Development published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Application In Synthesis of 3796-23-4.