One-pot ester and thioester formation mediated by pentafluoropyridine (PFP) was written by Beardmore, Liam N. D.;Cobb, Steven L.;Brittain, William D. G.. And the article was included in Organic & Biomolecular Chemistry.Related Products of 700-16-3 The following contents are mentioned in the article:
Herein, the pentafluoropyridine can be utilized to generate acyl fluorides in situ under mild conditions, and they can subsequently be used to generate a range of esters RC(O)OR1 (R = Ph, pyridin-2-yl, Et, etc.; R1 = Ph, t-Bu, pyridin-3-yl, etc.) and thioesters RC(O)SR2 (R2 = Ph, t-Bu, Bn, etc.). This methodol. offers a simple one-pot synthesis of esters and thioesters directly from parent carboxylic acids RC(O)OH. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Related Products of 700-16-3).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six è?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hçckel criteria for aromatic systems. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Related Products of 700-16-3