In 2019,Bioorganic Chemistry included an article by Benchekroun, Mohamed; Pachon-Angona, Irene; Luzet, Vincent; Martin, Helene; Oset-Gasque, Maria-Jesus; Marco-Contelles, Jose; Ismaili, Lhassane. SDS of cas: 128071-75-0. The article was titled 《Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction》. The information in the text is summarized as follows:
We report herein the synthesis antioxidant and Aβ anti-aggregation capacity of (E)-N-benzyl-N-[2-(benzylamino)-2-oxoethyl]-3-(aryl)acrylamides and related (R)-N-benzyl-N-(2-(benzylamino)-2-oxoethyl)-5-(1,2-dithiolan-3-yl)pentanamides 1-12. These compounds have been obtained, via Ugi four-component reaction, from modest to good yields. Their antioxidant anal., using the DPPH and ORAC assays, allowed us to identify compounds 8 and 9, as potent antioxidant agents, showing also strong Aβ1-40 self-aggregation inhibition, two biol. properties of interest in pathologies linked to the oxidative stress, such as Alzheimer’s disease. In the experimental materials used by the author, we found 2-Bromonicotinaldehyde(cas: 128071-75-0SDS of cas: 128071-75-0)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.SDS of cas: 128071-75-0