A new synthesis of symmetrical 2,5-disubstituted 1,3,4-oxadiazoles was written by Bentiss, Fouad;Lagrenee, Michel. And the article was included in Journal of Heterocyclic Chemistry in 1999.Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole This article mentions the following:
Title compounds I [R = (un)substituted phenyl; 2-, 3-, 4-pyridinyl; 2-thienyl] were prepared in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole).
2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Name: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole