Berger, Olivier published the artcilePhosphorus-Carbon Bond Formation: Palladium-Catalyzed Cross-Coupling of H-Phosphinates and Other P(O)H-Containing Compounds, Computed Properties of 39856-58-1, the publication is Advanced Synthesis & Catalysis (2013), 355(7), 1361-1373, database is CAplus.
Two generally applicable systems were developed for the cross-coupling of P(O)H compounds with Csp2-X and related partners. Pd catalysis using a ligand/additive combination, typically either xantphos/ethylene glycol or 1,1′-bis(diphenylphosphino)ferrocene/1,2-dimethoxyethane, with diisopropylethylamine as the base, proved to be generally useful for the synthesis of numerous P-C containing compounds E.g., reaction of RP(O)(OEt)H (R = octyl) with 2-bromopyridine in the presence of 2 mol% Pd(OAc)2/xantphos, toluene and ethylene glycol and (iPr)2NEt at 115° to give 93% yield of (Oct)P(O)(OEt)(2-pyridyl). Routinely, 2 mol% of catalyst are employed (less than half the amount typically employed in most other literature reports). In most cases, excellent results were obtained with a variety of electrophiles (RX, where R = alkenyl, allyl, alkynyl, etc.). The full account of the studies is disclosed, including tandem hydrophosphinylation/coupling and coupling/coupling for doubly catalytic P-C bond formation. The methodol. compares favorably with any existing literature report. The use of an additive appears to be a generally useful strategy to control the reactivity of phosphinylidene compounds
Advanced Synthesis & Catalysis published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Computed Properties of 39856-58-1.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem