Adding a certain compound to certain chemical reactions, such as: 1121-60-4, Picolinaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 1121-60-4, blongs to pyridine-derivatives compound. Product Details of 1121-60-4
General procedure: To a solution of 4-methoxybenzaldehyde (1mmol, 0.136 g) in dry DMF (5mL), hydroxylamine hydrochloride (3 mmol, 0.208 g) was added with stirring for 15 min at 120 C. HAP(at)AEPH2-SO3H nanocatalyst (8 mol-%, 0.08 g) was then added to the resultant solution. After completion of the reaction (which was monitored byTLC), cooling, and separation of the nanocatalyst by centrifugation, the reaction mixture was poured into water (10mL). The resulting mixture was extracted with ethyl acetate (310mL) and dried over sodium sulfate. After evaporation of the solvent, the crude product was purified by thin-layer chromatography using n-hexane/ethyl acetate (4 : 1) as eluent to afford 4-methoxybenzonitrile (0.130 g, 98%).
The synthetic route of 1121-60-4 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Masjed, Samane Memar; Akhlaghinia, Batool; Zarghani, Monireh; Razavi, Nasrin; Australian Journal of Chemistry; vol. 70; 1; (2017); p. 33 – 43;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem