Brief introduction of 145100-50-1

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 145100-50-1, 1,1,1-Trifluoro-N-(pyridin-2-yl)-N-((trifluoromethyl)sulfonyl)methanesulfonamide.

145100-50-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 145100-50-1, name is 1,1,1-Trifluoro-N-(pyridin-2-yl)-N-((trifluoromethyl)sulfonyl)methanesulfonamide. This compound has unique chemical properties. The synthetic route is as follows.

To a solution of phenol, obtained as above, dissolved in CH2Cl2 (30 mL) were addedN-(2-pyridyl)bis(trifluoromethanesulfonimide) (1.83 g, 5.12 mmol) and triethylamine(1.07 mL, 7.65 mmol) at room temperature. After stirring for 6 h at the same temperature,to the mixture was added an aqueous saturated solution of NH4Cl (30 mL). The mixture was extracted with CH2Cl2 (50 mL ¡Á 3), and the combined organic extract was dried (Na2SO4), and after filtration, the filtrate was concentrated under reduced pressure. The residue was purified by flash column chromatography (silica-gel 100 g, n-hexane/CH2Cl2= 4/6 to 1/9) to give bis(3,5-bis(trifluoromethyl)phenyl)(2-triflyloxyphenyl)phosphineoxide (1c) (2.27 g, 3.25 mmol, 63.7% in two steps) as a colorless solid.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 145100-50-1, 1,1,1-Trifluoro-N-(pyridin-2-yl)-N-((trifluoromethyl)sulfonyl)methanesulfonamide.

Reference:
Article; Nishiyama, Yoshitake; Kamada, Shuhei; Yoshida, Suguru; Hosoya, Takamitsu; Chemistry Letters; vol. 47; 9; (2018); p. 1216 – 1219;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem