Electric Literature of 69045-78-9 , The common heterocyclic compound, 69045-78-9, name is 2-Chloro-5-(trichloromethyl)pyridine, molecular formula is C6H3Cl4N, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
The liquid was found to contain 17 ppm tungsten. The solid (1.4 grams) was used to catalyze the chlorination of 187.6 grams of 2-chloro-5-trichloromethylpyridine at 200 C. and ambient pressure. In 98 hours, 77.5 weight percent of 2,3-dichloro-5-trichloromethylpyridine was obtained.
The synthetic route of 69045-78-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; The Dow Chemical Company; US4532111; (1985); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem