Related Products of 34392-85-3, Adding some certain compound to certain chemical reactions, such as: 34392-85-3, name is 3-Amino-2-chloro-6-methoxypyridine,molecular formula is C6H7ClN2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 34392-85-3.
Bring a solution of 2-chloro-6-methoxy-3-nitro-pyridine (2. 8 g, 0. 018 mol) in 75% H2SO4 (15 mL) to 0C using an ice bath. Slowly add a solution of NaN02 in water (5 mL) to the reaction mixture and stir for 30 minutes. Add three molar equivalents of CuCI in concentrated HCl and stir for 15 minutes. Heat the mixture at 80C for 30 minutes. Pour onto ice, extract the aqueous with ethyl acetate, dry the organic layer (NA2SO4) and concentrate under reduced pressure. Purify using flash column chromatography (hexanes to 10% ethyl acetate/hexanes eluent) to afford the title compound.
According to the analysis of related databases, 34392-85-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NEUROGEN CORPORATION; WO2005/7648; (2005); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem