Adding a certain compound to certain chemical reactions, such as: 637348-81-3, 3-Bromo-5-iodopyridin-2-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 637348-81-3, blongs to pyridine-derivatives compound. Product Details of 637348-81-3
Example 214b 3-Bromo-5-iodo-1-methylpyridin-2(1H)-one 214b A 100-mL single-neck round-bottomed flask equipped with a magnetic stirrer was charged with DMF (50 mL), 214a (6.0 g, 20.0 mmol), iodomethane (4.26 g, 30.0 mmol), and K2CO3 (5.52 g, 40.0 mmol). The mixture was stirred at room temperature for 2 h and diluted with water (200 mL). The resulting white solid was collected by filtration to afford 214b (5.97 g, 95%) as a white solid. MS-ESI: [M+H]+ 314
At the same time, in my other blogs, there are other synthetic methods of this type of compound,637348-81-3, 3-Bromo-5-iodopyridin-2-ol, and friends who are interested can also refer to it.
Reference:
Patent; F.Hoffmann-La Roche AG; CRAWFORD, James John; ORTWINE, Daniel Fred; WEI, BinQing; YOUNG, Wendy B.; EP2773638; (2015); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem