The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 94220-38-9, name is 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine. This compound has unique chemical properties. The synthetic route is as follows. Product Details of 94220-38-9
EXAMPLE 24 7-(3,4-Dichloroanilino)-5-methyl-1H-pyrazolo[4,3-b]pyridine (24) STR37 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine (1.5 g) and 3,4-dichloroaniline (1.45 g) were heated under reflux in ethanol (90 ml) for 48 h. The solvent was removed in vacuo to yield a yellow solid which was suspended in water and the pH adjusted to 7.8. The solid was filtered off, washed with water, and dried to yield the 7-(3,4-dichloroanilino)-compound (2.27 g, 87%) which was recrystallized from ethanol (charcoal) to yield a white amorphous solid m.p. 273 (dec.). (Found: C, 53.1; H, 3.5; N, 19.3; Cl, 24.1. C13 H10 N4 Cl2 requires C, 53.3; H, 3.45; N, 19.1; Cl, 24.2%), numax. 3400-2250 (N-H), 1630, 1580, 1530, 1410, 1400, 1310, 1135, 955, 850, 810 cm-1, delta (CF3 COOH) 2.76 (3H, s, 5-CH3), 6.86 (1H, s, 6-H), 7.49 (3H, m, aromatic protons), 8.46 (1H, s, 3-H), 9.47 (2H, s, N? H2), total proton count 10.
With the rapid development of chemical substances, we look forward to future research findings about 94220-38-9.
Reference:
Patent; Beecham Group, p.l.c.; US4559348; (1985); A;,
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